By L.O. Baker,Frederick A. Valeriote,Voravit Ratanatharathorn

This yr notes significant adjustments within the annual Detroit melanoma Symposium. the 1st is our goal of choosing most sensible­ ics of wide curiosity to the melanoma group and studying the topic from either a simple laboratory and medical standpoint. during this approach, the significance of either components of melanoma learn are famous and the interaction among them emphasised. additional, we think that Symposia equivalent to this act to stimulate the fundamental scientist and clinician to proceed their reviews with the understand­ ledge of the impression that every has upon the opposite and the nec­ essary cooperation required to resolve the melanoma challenge. the second one switch is the e-book of this Symposium. The pre­ vious 16 weren't dedicated to manuscript shape. Given the switch in structure and purpose of the sequence, we think that this and next volumes will make vital contributions to the melanoma literature. the subject of "Biology and remedy of Acute Leukemia" was once selected for the 1st Symposium as a result of its ancient signif­ icance in melanoma chemotherapy. The healing motive for human leukemia is the results of realizing the fundamental tumor biology mostly derived from transplantable leukemias in exper­ imental animals. it's via those versions, as mentioned via Dr. Fred Valeriote, that we discovered the mobile kinetics of leukemia, the antileukemic results of latest brokers and the ef­ fect of development perturbation by way of a number of chemotherapeutic brokers and their combinations.

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