By Kirk L. Hamilton,Daniel C Devor

This publication sheds new gentle at the body structure, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the fundamental mobile versions and capabilities via a compelling medical point of view, addressing features from the laboratory bench to the bedside. the person chapters, written by way of top scientists and clinicians, discover particular ion channels and transporters situated within the epithelial tissues of the kidney, gut, pancreas and respiration tract, all of which play an important half in conserving homeostasis. extra issues contain the basics of epithelial delivery; mathematical modeling of ion shipping; phone quantity legislation; membrane protein folding and trafficking; transepithelial delivery services; and finally, a dialogue of shipping proteins as capability pharmacological objectives with a spotlight at the pharmacology of potassium channels.

 

Show description

Read Online or Download Ion Channels and Transporters of Epithelia in Health and Disease (Physiology in Health and Disease) PDF

Similar cell biology books

Cell Biology of Plant Nematode Parasitism: 15 (Plant Cell Monographs)

Plant-parasitic nematodes are one of the such a lot harmful plant pathogens, inflicting huge, immense losses to agronomic plants all over the world. This publication presents an up to date overview of study relating to of an important nematode pests, root-knot and cyst nematodes. Chapters conceal early plant-nematode interactions, id of nematode proteins very important within the institution of nematode feeding websites, and category of biochemical and signaling pathways major within the improvement of specialised feeding websites within the host.

Constitutive Activity in Receptors and Other Proteins, Part B: 485 (Methods in Enzymology)

This quantity of equipment in Enzymology covers the present technique for the detection and overview of constitutively lively proteins. The chapters written by way of specialist authors who're leaders within the box, offer tricks and methods now not on hand in basic study guides. it really is broadly referenced, with important figures and tables through the quantity.

Studies on Retinal and Choroidal Disorders (Oxidative Stress in Applied Basic Research and Clinical Practice)

Stories on Retinal and Choroidal issues examines the function that oxidative and nitrosative rigidity performs within the complicated body structure and pathophysiology of the retina and choroid.  either the elemental technology researcher and the scientific practitioner can use this booklet as a consultant to the present knowing of retinal and choroidal mobile mechanisms interested in getting older and ailment.

Proteases in Apoptosis: Pathways, Protocols and Translational Advances

This publication presents a entire evaluate of the proteases taken with programmed cellphone demise. It offers a targeted but wide dialogue on proteolytic enzymes resembling caspases, HtrAs, granzymes, calpains and cathepsins in addition to laboratory protocols relating to enzymology and apoptosis. Mouse version structures and non-invasive imaging thoughts in apoptosis-related illnesses reminiscent of melanoma and neurodegeneration also are lined during this e-book.

Extra info for Ion Channels and Transporters of Epithelia in Health and Disease (Physiology in Health and Disease)

Example text

Download PDF sample

Rated 4.34 of 5 – based on 4 votes