By Fiorenzo Stirpe,Douglas Lappi

this crucial reference presents updated info on all elements of ribosome-inactivating proteins (RIPs). together with a listing of all recognized RIPs, their distribution in nature, constitution, genetics and chemical and immunological homes, this reference covers mechanisms of motion, together with the enzymatic task on a number of polynucleotide substrates; the interplay with, and access into cells; the toxicity to animals, together with the pathology of poisoning; and the immunomodulatory and allergenic task. The ebook additional emphasizes using immunotoxins and different conjugates in scientific trials for the remedy of melanoma and intractable pain.

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