By Lorenza (Ed.) González-Mariscal,Lorenza González-Mariscal

Tight Junctions presents a cutting-edge view on Tight Junctions (TJs). beginning with an research of the evolutionary improvement of a transporting epithelium in early metazoans, the ebook describes the present TJ constitution and serve as info, together with the current day facts assisting the presence of ion channels inside TJs. specific emphasis is given to the teachings discovered from cellphone tradition types, mutant mice and heritable human ailments. to focus on the trendy imaginative and prescient of TJs as signaling complexes, the booklet discusses the institution of TJs in the course of improvement, the shuttling of TJ proteins among the plasma membrane and the nucleus, and the function of TJ proteins in mobile cycle development and cancer.

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